Faculty Name:	Mr. AR MAHESH
Designation :	Assistant Professor

Mr. AR Mahesh graduated B.Pharm in Dayananda Sagar College of Pharmacy M.Pharm Pharmaceutical Chemistry from RGUHS, Bengaluru, MBA in Pharma Business Management from ICFAI, Tripura, and currently perusing Research studies (PhD) under RGUHS. His passion for research has driven up to acquire a 7 Lakh grant from RGUHS, Bengaluru as a Co-Investigator for research work in the arena synthetic chemistry of novel Anticancer Agents.
On his regard he has two prestigious awards namely Academic Excellence Award 2019 by Institute of Scholars, an MSME enterprise, Government of India and Excellence Teaching in Higher Education Award 2020 by DK International Research Foundation, Perambalur, Tamilnadu, India. As an intellectual asset, an outcome of my research works has been published in the Scopus/ Web of Science indexed National and International Journals (20+ scientific publications). He is currently Member editorial of SAS Journals and Rubatosis Publications and peer reviewer in more than 10 national and international journals .
He was awarded Grade-A for the Continuous education program conducted by Indian Institute of Science, Bengaluru and acquired a proficiency Skill in 1D and 2D NMR Spectroscopy & their applications in Structure Biology. He has expanded my interest to the current IT related application in drug design with cognisance on molecular modelling of new chemical entities.
He is an invitee as a resource person on the lateral domains of pharmaceutical sciences such as IPR, Soft skill trainer for UG and PG Students in reputed institutes like KCP, PESCP, RGUHS, Oxbridge College of Pharmacy, Bengaluru PS College of Pharmacy, Krishnagiri, Bengaluru and also designated as at trainer in Faculty Development Program sponsored by RGUHS & APTI, Bengaluru.
As a part of career excellence, he has guided the undergraduate students on making a scientific writing of research work they have carried on. As an academician he initiated his career as Lecturer in RGUHS affiliated institute, Krupanidhi College of Pharmacy and currently is Assistant Professor in College of Pharmaceutical Sciences, Dayananda Sagar University Since 2014.
On prospect of knowledge exchange and development he is a Life member of Association of Pharmaceutical Teachers of India, Foundation for Health and Environment Research, International Society for Pharmacoeconomics and Outcomes Research, ISPOR, Institute of Scholars, India & Karnataka State Pharmacy Council.

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Recent Awards:

1. “Academic Excellence Award 2019” by ‘Institute of Scholars’ recognized by Ministry of MSME, India, in recognition of valuable contribution to the academic community and students.

Editorial Board Member:

1. Rubatosis Publications, since 21/03/2018.
2. International Journal of Multidisciplinary Research and Publications, since 21/04/2018

Professional Registration Certification:

1. Registered Pharmacist under Karnataka State Pharmacy Council, India since 28-Mar-2009.
2. Lifetime Member of Institute of Scholars, Recognized by Ministry of MSME, since September, 2019.
3. Member of ISPOR, Since September, 2019
4. Life Member of Foundation for Health and Environment Research, Since September, 2019

Research:

1. Research Interests
   • Synthesis of Novel Anticancer agents,
   • Molecular Modelling and Docking studies of novel anticancer agents.
2. Research Grants: Annexture-3

   Sl. No.	Project Title	Sponsoring Agency	Date of Sanction	Project Cost	PI/Co-PI/Ongoing/ Completed
   1	‘Synthesis and evaluation of Nitrogen Mustard linked benzofuranone derivatives as possible alkylating anticancer agents’	RGUHS	06/01/2016	7,00,000	Co-PI/Ongoing

3. Industry interaction:
   • Completed one year “Internship programme” and dissertation project in Department of Phytochemistry research at Natural Remedies Pvt., Ltd., Bangalore.
4. Publications
   • National/International Publications: 16 (Annexture-4)
   • Poster Presentations in Conferences: 05 (Annexture-5)
   • Conferences Attended: 32 (Annexture-6)

Other Achievements:

1. Proficiency course in 1D and 2D NMR Spectroscopy: Applications in Structure Biology. IISc, Bengaluru (Jan-May, 2016) [secured A-Grade]
2. Resource person in “Soft Skills and Leadership” in Krupanidhi College of Pharmacy on 19-06-2012 for UG and PG students of Pharmacy.

3. Resource person in “Short Course in Education methodology” Conducted by RGUHS in collaboration with APTI for teachers of Pharmacy Faculty.

   Roles:

   • Headed a training session on “Question paper Setting” on 21st Mar, 2016
   • Headed a training session on “Objective structured practical Examination” on 29th Mar, 2016.
   • Evaluator for various micro teaching sessions of the course.
4. Resource person in Guest Lecture was given on the topic “The Patents Act” at PES College of Pharmacy on 24th Mar, 2016.
5. Resource person in five days Faculty Development Program on “Managing Stress in Teaching Profession” held at Dayananda Sagar University, Bengaluru from 9th -13th January, 2017
6. Resource person in Guest Lecture organized by PES College of Pharmacy on 24th Mar, 2017 Topic “Magic remedies and objectional advertisements act”.
7. Resource person in Guest Lecture organized by College of Pharmaceutical Sciences, Dayananda Sagar University on 27th Oct, 2019, Topic: Application of Artificial Intelligence in Healthcare.
8. E-Poster Evaluator, in RGUHS sponsored National Conference on “Cosmeceutical Technology” RR College of Pharmacy on 13th and 14th March, 2020.

Present Research Work

An attempt will be made to synthesize some heterocyclic compounds containing Nitrogen mustards linked to Aurones and to study their possible cytotoxicity and anticancer activity will be evaluated.

• Synthesis of Nitrogen mustard linked Aurones based on reported methods.
• Purification and characterization of the structures of newly synthesized compounds by TLC, UV, FTIR ,1H NMR, 13C NMR and CHN analysis methods

The rapid assembly of molecular diversity is important goal of Synthetic Organic Chemistry and one of the key paradigms of modern drug discovery. One approach to address this challenge involves development of newer molecules in which a few reactants are combined together in a single reaction flask to generate a product incorporating most of the atoms contained in the starting materials. Diversity can be achieved either by varying each component or changing the reaction conditions. The biological activity and development of novel drugs with unique properties. The Aurones and Nitrogen mustards possess significant pharmacological and biological activities such as alkalyting, cytotoxic, antitumor, anti-inflammatory and other diseases.

Publications

1. Vimal John Samuel, Komal Kulkarni, Agasa Ramu Mahesh, Drug Utilization Pattern of Cephalosporins in In-Patient Departments of Tertiary Care Hospital. Journal of Pharmaceutical Sciences and Research. 2019;11(6), 2398-2401.
2. Vimal John Samuel, AgasaRamu Mahesh, VedigounderMurugan, Phytochemical and pharmacological aspects of Tephrosia genus: A brief review. Journal of Applied Pharmaceutical Science, 2019; 9(03), 117-125
3. Vimal John Samuel and A. R. Mahesh , In- Vitro Antioxidant Properties, Acute And Subacute Toxicity Studies Of TephrosiaCalophylla On Albino Wistar Rats. International Journal of Pharmaceutical Sciences and Research, 2019; 10(6): 1000-07.
4. KB Premakumari, AR Mahesh, V Murugan, V Ezhilarasan. Simultaneous estimation of paracetamol and zaltoprofen in pharmaceutical dosage form by HPTLC. http://www.anvpublication.org/Download_Acceptance.aspx?PID=1916200209899803.
5. AsalTanhaeiSaeid, Fereshteh Jaferi, AR Mahesh, Ali Alipour, Komal Kulkarni, A Retrospective, Observational Study Effect of Polypharmacy and Drug Interactions in Elderly Patients. Saudi Journal of Medical and Pharmaceutical Sciences, 2019; 5(2): 147-153.
6. Kalpana Divekar, Sushma KR, AR Mahesh, Selectivity of Plants and Microbial Reduction of Ketones. Sch. Acad. J. Pharm. Jan 2018;7(1):26-35.
7. V Murugan, Shrideep Bhattacharjee, AR Mahesh, Synthesis and characterization of N-N- {Bis(2′-Chloroethylamino)- nitroso}-2-benzylidene-1-benzofuran derivatives as antileukemic agents. Am. J. Pharm Health Res, 2016;4(7).
8. Mahesh AR, Samuel YamtaMshelia and Vimal John Samuel, Therapeutic activities of Aurone, An appositely active molecule-A Review. World Journal of Pharmacy and Pharmaceutical Sciences. 2016: 5(7):668-82.
9. Mahesh AR, Murugan V, Synthesis of a biologically pertinent molecule, Aurone-An extensive review. European Journal of Biomedical & Pharmaceutical Sciences. 2016: 3(1):112-16.
10. M Somashekhar, Naira Nayeem, Mahesh AR. Botanical study of four ficus species of family Moraceae: A Review. International Journal of Universal Pharmacy and Bio Sciences, 2013; 2(6):558-570.
11. Somashekhar M, Mahesh AR. Synthesis and antimicrobial activity of piperazine derivatives. Am.J.Pharm Tech. 2013; 3(4):640-648.
12. Somashekhar M, Mahesh AR, Basavaraj Sonnad. Synthesis and antimicrobial activity of of 4-(morpholin-4-yl) benzohydrazide derivatives. World Journal of Pharmacy and Pharmaceutical Sciences, 2013; 2(4):2011-2020.
13. Manish K, Mahesh AR, Somashekhar M.   International Journal of Pharma Research and Review, 2013; 2(8).
14. Mahesh AR, Ranganath Mk, Harish Kumar DR, Enrichment of Flavanoids from the methanolic Extract of BoerhaaviaDiffusa Roots by Partitioning Technique. Research Journal of Chemical Sciences, 2013:3(1),43-47.
15. Hitesh HS, Mayukh B, Mahesh AR. Isolation and characterization of chemical constituents of aerial parts of Lantana Camara. 01 2012; 1(6):198-207.
16. AR Mahesh, Harish Kumar, K, Raviraj Anand Devkar. Detail Study on BoerhaaviaDiffusa Plant for its Medicinal Importance-A Review, Research Journal of Pharmaceutical Sciences. 2012; 1(1):28-36.

Presentations

1. Presented a poster “Simultaneous estimation of paracetamol and zaltoprofen in pharmaceutical dosage form by HPTLC” in international conference Krupacon-2018, Krupanidhi College of Pharmacy, Bengaluru, 2018.
2. Presented a poster “Neonatal Infections - A Review” in National Conference on "Advances in Pharmacy Practice", NET College of Pharmacy, Raichur. 28th-29th Nov, 2013.
3. Presented a poster “Synthesis and Hydrolytic kinetic study of derived antihypertensive codrugs” 3rd International Pharmaceutical Conference on “Current status and future perspective in Pharmaceutical Sciences”, PESCP.19th-20th August 2011.
4. Presented a poster “Synthesis and Hydrolytic kinetic study of some Antihypertensive Co-Drugs” in 63rd IPC, Bangalore. 16th -18th December 2011.
5. Presented a poster “Synthesis of some Co-Drugs of Propranalol and other antihypertensive drug via Anhydride Bridge and their hydrolytic kinetic study” in Indo-US Symposium on “Frontiers in Medicinal Chemistry and Drug Discovery” April 21st-23rd 2011.

Seminars/ Conferences/ Workshops Attended:

Sl No.	Date	Place	Title	Organizing Agency	No.Of Days
1	13-03-2020, 14-03-2020	RR College of Pharmacy, Bengaluru	Cosmeceutical Technology	RGUHS, RR College of Pharmacy, Bengaluru	2
2	25-03-2019	Vishveshwarapura Institute of Pharmaceutical Sciences	Short Course on Teaching Methodologies	RGUHS, Karnataka	2
3	16-02-2019	RR College of Pharmacy	National Workshop on Computer Aided Drug Development	RGUHS, RR Institutions, Bengaluru	1
4	22-01-2019	Zastra Innovations	One Day International Symposium on Streamlining Drug Design	Regenta Palace, Bengaluru	1
5	17-12-2018	Dayananda sagar University	Challenges and Opportunities for clinical pharmacists	Dayananda Sagar University, Bengaluru	2
6	12-10-2018	Krupanidhi College of Pharmacy,Bengaluru	International Conference on drug development and clinical research: current scenario and opportunities	Krupanidhi College of Pharmacy, Bengaluru	2
7	29-08-2018	Dayananda Sagar University	Targeted Cancer Therapy and ResearchAdvances and Challenges	Dayananda Sagar University, Bengaluru	1
8	19-08-2018	College of Pharmaceutical Sciences	Targeted Cancer Therapy & Research- Advances & Challenges	Dayananda Sagar University	1
9	25-04-2018	College of Pharmaceutical Sciences, DSU	Career Opportunities in Clinical Research & Pharmacovigilance	Dayananda Sagar UNiversity	1
10	15-02-2018	Ramiah University	Application of computational tools in drug design & formulation development	Ramaiah University	1
11	14-07-2017	Krupanidhi College of Pharmacy	Workshop on sensitisation of syllabus for B.Pharm & M.Pharm Courses	Pharmacy Council of India	1
12	09-01-2017	College of Pharmaceutical Sciences, Dayananda Sagar University	Managing Stress In Teaching Profession	College of Pharmaceutical Sciences, Dayananda Sagar University	5
13	14-11-2016	Goa College of Pharmacy, PanjimGoa	1.5 Day Professional Development Program: Intellectual Property for Industry and Academia Professionals: Training the Trainers	G-CEIP	2
14	05-08-2016	BMS College of Engineering, Bengaluru	One Day National Symposium on Fundamentals of Drug Discovery Process:Industrial Perspective	Department of Chemistry & Biotechnology,BMSCE	1
15	26-02-2016	KLE University, Bengaluru	Workshop on Interpretation of Spectra- A Practical Approach	KLE University	1
16	01-01-2016	IISc	1D &2D NMR Spectroscopy: Applications in Structure Biology	CEE- Proficience Programme-IISc	20
17	05-10-2015	Al-Ameen College of Pharmacy, Bengaluru	National Level Workshop on Rational Approach on Drug Design and Discovery using CADD	Vlife, Al-Ameen College of Pharmacy	2
18	29-09-2015	Rajiv Gandhi University of Health Sciences	Research Methodology CME & Workshop	RGUHS, Karnataka	2
19	29-11-2013	NET Pharmacy College, Raichur	National Conference on Advances in Pharmacy Practice	RGUHS, Karnataka	2
20	16-09-2013	Acharya & BM Reddy College of Pharmacy,Bengalur	FDP on Computer Aided Drug Design	ACTE	13
21	16-12-2011	Bangalore International Exhibition Centre	63rd Indian Pharmaceutical Congress	Indian Pharmaceutical Congress	3
22	14-12-2011	Al-Ameen College of Pharmacy, Bengaluru	Pre-Conference workshop on the basic concepts of Scientific Research and Scientific Communication of 63rd IPC	Indian Pharmaceutical Congress	2
23	19-08-2011	PES College of Pharmacy	Current Status & Future Perspective in Pharmaceutical Sciences	DST, CSIR, ICMR, RGUHS, AICTE	2
24	21-04-2011	JSS University, Mysore	Indo-US Symposium on Frontiers in Medicinal Chemistry and Drug Discovery	American Chemical Society	3
25	11-02-2011	Dayananda Sagar College of Pharmacy	Principles, Applications and Current Developments in 1H NMR, 13C NMR and aMass Spectroscopy	DST, RGUHS	2
26	03-12-2010	Dayananda Sagar College of Pharmacy	Standardization and evaluation of Herbal Drugs	RGUHS, Karnataka	1
27	21-05-2010	DSCDS & Hospital	Infection control in Health Care Setting	Indian Dental Association	1
28	31-03-2010	Dayananda Sagar College of Pharmacy	Recent Trends in Molecular Pharmacology and Drug Designing	DST	2
29	02-02-2008	Dayananda Sagar College of Pharmacy	Clinical Research- Advances and Opportunities	RGUHS	1
30	14-12-2007	Dayananda Sagar College of Pharmacy	Synthesis of Heterocyclic Compounds using Microwave Technique	RGUHS, Karnataka	1